The title is a play on the phrase "From bad to worse."
Roberta sneaks out to a club called T.G.I. Cheney's while in Washington D.C.. The club name is a reference to former United States Vice President Dick Cheney, as well as the restaurant "T.G.I. Friday's".
In one scene, Cleveland is shown on a fly's body. He is then later killed by a fly on Cleveland's body. This is a reference to the movie The Fly.